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caries
Localized disease that causes decay and cavities in teeth. It begins at the tooth's surface and may penetrate the dentin and the pulp cavity. Microorganisms in the mouth are believed to consume sugars and produce acids that eat away at tooth enamel. The dentin's protein structure is then destroyed by enzymes. Diet, general health, structural tooth defects, and heredity affect the risk of having caries. Prevention involves avoiding excessive sweets, brushing and flossing the teeth, and having regular dental care. Treatment includes restoration of teeth with cavities. Fluoridation of water can reduce the occurrence of caries by as much as 65%.
rabies
Acute, usually fatal infectious disease of warm-blooded animals that attacks the central nervous system. It is spread by contact with an infected animal's saliva, usually from a bite. The rhabdovirus that causes it spreads along nerve tissue from the wound to the brain. Symptoms usually appear four to six weeks later, often beginning with irritability and aggressiveness. Wild animals lose their fear of humans but are easily provoked to bite, as are pets. Depression and paralysis soon follow. Death usually comes three to five days after symptoms begin. In humans, death can result from a seizure in the early phase even before symptoms of central-nervous-system depression develop. One name for rabies, hydrophobia ("fear of water"), comes from painful throat contraction on trying to swallow. If not treated in time (within a day or two) with a serum containing antibodies and then a series of vaccinations, rabies in humans is almost always fatal. Immediate cleansing of animal bites with soap and water can remove much of the virus.
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